INDIANAPOLIS (AP) — The Indianapolis Colts have ruled out both of their usual starting guards for Thursday night’s game in Houston.

Left guard Jack Mewhort and right guard Hugh Thornton have not practiced all week because of injuries. Mewhort will miss his second straight game with an ankle injury. Thornton is out after injuring his back in Sunday’s victory over Baltimore.

Coach Chuck Pagano has not said who the replacements will be, but it’s possible Lance Louis will take Mewhort’s spot and either A.Q. Shipley or Joe Reitz will step in for Thornton.

Indy (3-2) also has ruled out defensive tackle Arthur Jones and cornerback Darius Butler, who both have ankle injuries.

Inside linebacker Jerrell Feeman (hamstring) is listed as probable against the Texans (3-2).

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