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One Day, A Pill Might Offer You the Same Benefits As Exercise

By U.S. News & World Report

Imagine a typical morning: You groggily wake up, brush your teeth, eat breakfast, take your exercise pill:

Wait, what?

It may not be so far-fetched, as Salk Institute research published this week in Cell Metabolism found that such a drug increased athletic endurance by 70 percent in mice.

The drug activates a genetic pathway that usually occurs from running, enabling the mice to experience similar outcomes like increased stamina and fat loss, reports Fox News. The best part? It didn’t require any movement.

This research builds on earlier work, in which researchers discovered sedentary genetically-engineered mice that had a permanently-activated gene (known as PPAR delta, or PPARD) grew into long-distance runners. They were impervious to weight gain and were more responsive to insulin, which regulates your blood sugar and lets your body absorb carbohydrates for energy use. A chemical compound, GW1516, offered the same PPARD activation, though it didn’t alter endurance.

The new study gave the sedentary mice the GW1516 dose for 8 weeks as opposed to four weeks. While the control group mice could only run 160 minutes before exhaustion took hold, the drug gave mice a 70 percent leg up at 270 minutes. And the mice were still insulin-responsive and weight gain-resistant.

“This study suggests that burning fat is less a driver of endurance than a compensatory mechanism to conserve glucose,” Michael Downes, a senior scientist at Salk and study author said in a statement. “PPARD is suppressing all the points that are involved in sugar metabolism in the muscle so glucose can be redirected to the brain, thereby preserving brain function.”

Pharmaceutical companies have shown interest in the drug for use in human clinical trials. Researchers see a possible prescription drug use for those with obesity or type 2 diabetes to burn more fat in addition to helping patients’ fitness before or after any surgery they may undergo.

Still, such a pill wouldn’t be immune to skepticism.

“Personally, I am not certain that such a pill would be possible,” Ali Tavassoli, a Southampton University professor of chemical biology told The Guardian. “There’s a big difference between showing in an organism that you can mimic exercise over the short-term and demonstrating the long-term effects of doing this.”

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One Day, A Pill Might Offer You the Same Benefits As Exercise originally appeared on usnews.com

Don’t Settle for Student Loans to Pay for Online Education

By WTOP Staff
Online college programs are becoming a more popular choice for prospective students, with one study finding that more than 6 million students enrolled in at least one online course in fall 2015. The popularity of these courses can be attributed in part to their flexibility with working adults' schedules, students' ability to progress more quickly through online programs and, oftentimes, cheaper tuition. [See 10 low-cost online bachelor's programs for out-of-state students.]Online degrees can be beneficial to many college students, but some studies have shown online learners complete their programs at lower rates than students at traditional brick-and-mortar campuses. Individuals with student loans but no degree comprise two-thirds of defaulted borrowers. Though these numbers are not encouraging, just like for traditional programs, there are ways to reduce how much you'll need to borrow for an online program to ensure you won't become one of these statistics. Don't just settle on borrowing student loans to cover the whole cost of your program and living expenses. Instead, start thinking about how to cut costs and cover your balance in different ways, such as the following. -- Grants and scholarships: Even though you are taking an online course, you can still apply and receive grants and scholarships. But your first step should be to complete the Free Application for Federal Student Aid, commonly referred to as the FAFSA, which will allow you to receive a Pell Grant if your expected family contribution is low enough. The EFC criteria and award amounts are adjusted annually, but the 2017-2018 academic year awards range from $606 to $5,920, which could significantly lower the amount you borrow annually. Your next step is to apply for scholarships. You can start by checking online scholarship search engines, such as the Salt Scholarship Search, College Board's BigFuture and Peterson's. But don't forget to take advantage of local organizations and your school's financial aid office. Both may offer scholarships that you can't find with a national scholarship search. [Review these 10 sites to kick off your scholarship search.]For instance, organizations like the Elks Club, Knights of Columbus or the Rotary Club typically offer scholarships annually to local students. Just because you're going to school online doesn't mean you're ineligible. Visit your local library for scholarship listings, and ask around town. You might be surprised how many local organizations offer scholarships. While these scholarships typically aren't large, every little bit counts. Each dollar you receive in a scholarship is a dollar you don't have to borrow and pay interest on. -- Work-study: Another option for online students may be work-study awards. Not all students enrolled in online programs are eligible, but students at some schools -- including, for example, SUNY Empire State College and Liberty University -- are. Work-study awards are not given upfront like scholarships and grants. In most cases, they are an offer to earn up to the awarded amount if you secure an eligible work-study job. While there is a misconception that all work-study jobs must be on campus, students can work for off-campus, nonprofit or public employers as long as the work is in the public's interest. You may be able to work for a for-profit employer if the job is relevant to your course of study. No matter who the outside employer is, it will need to have an established agreement with your college for you to receive work-study funds. Remember, to be eligible for federal financial aid, you must be enrolled and pursuing a degree or certificate. If you're not working toward a credential, Pell Grants and work-study won't be option, but you may still be able to take advantage of private scholarships -- just be sure to read the eligibility criteria carefully. [Explore what to know about financial aid in online programs.]-- Pay as you go: One of the great benefits to enrolling online is the flexible schedule, which can allow you to complete your college coursework around your responsibilities. But prospective students often overlook using their part- or full-time job earnings as an option for paying for college. Almost 80 percent of college students in 2015 worked at least part time while attending classes, according to the National Center for Education Statistics. By budgeting and thinking strategically about your college costs, you can likely reduce your dependence on student loans by paying a portion out of pocket. Many -- but not all -- online programs are less expensive than traditional programs and often have shorter payment periods. Six, eight or 10 weeks are common course durations. Because of the frequency of payments in an online setting, you may be well-placed to pay as you go and possibly avoid borrowing altogether. Attending college online and avoiding student loans may be challenging, but if you are willing to put in the effort, you can limit the amount you need to borrow. More from U.S. News Q&A: Understanding Student Loan Discharge Eligibility Student Loan Refinancing Isn't Right for All Borrowers
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